Colchicine

From Journal of Medical Case Reports:
Abstract
Background: Colchicine is used in the treatment and prophylaxis of gout. It possesses a narrow
therapeutic window, frequently resulting in dose-limiting gastrointestinal side-effects such as
diarrhoea and emesis. As colchicine is a cellular anti-mitotic agent, the most serious effects include
myelosuppression, myoneuropathy and multiple organ failure. This occurs with intentional
overdose or with therapeutic [...]